Normally, only a small amount of protein is excreted in urine.

The 24-hour urine protein test provides an accurate measure of protein loss compared to a random urine sample.

Clinical uses include:

Detecting proteinuria (excess protein in urine).

Monitoring kidney disease progression.

Evaluating conditions such as diabetes, hypertension, glomerulonephritis, nephrotic syndrome, and lupus.

Assessing response to treatment in renal disorders.

The test requires collecting all urine passed in 24 hours in a special container.

Analyte: Total protein concentration in 24-hour urine.

Normal Range: Typically < 150 mg/24 hrs (may vary by lab).

High Protein Excretion:

May indicate kidney disease (glomerular or tubular damage).

Can be associated with diabetes, hypertension, infections, autoimmune diseases, or nephrotic syndrome.

Clinical Use:

Detects and quantifies proteinuria.

Differentiates between mild, moderate, and severe kidney damage.

Provides supportive information for diagnosis and monitoring of renal and systemic diseases.