Hepatitis C virus (HCV) is a blood-borne virus that primarily affects the liver.

The quantitative RNA test detects and measures the exact amount of viral RNA in blood.

Clinical uses include:

Confirming active HCV infection after a positive antibody test.

Determining baseline viral load before starting treatment.

Monitoring response to antiviral therapy.

Assessing risk of disease progression (chronic hepatitis, cirrhosis, hepatocellular carcinoma).

The test is performed using real-time PCR (polymerase chain reaction) methods.

Analyte: Hepatitis C virus RNA (viral load).

Normal Result: Undetectable (no HCV RNA present).

Abnormal Result: Detectable viral RNA → indicates active infection.

Clinical Use:

Confirms ongoing HCV infection.

Quantifies viral load for treatment planning.

Monitors effectiveness of antiviral therapy.

Helps predict long-term outcomes in chronic hepatitis C.