rimary biliary cholangitis (PBC), a chronic autoimmune liver disease.

Clinical uses include:

Confirming diagnosis of PBC.

Differentiating autoimmune liver disease from other causes of liver dysfunction.

Supporting evaluation of patients with cholestatic liver enzyme abnormalities.

The test is performed using a blood sample, typically via ELISA or immunofluorescence methods.

Analyte: Anti-mitochondrial antibodies in blood serum.

Normal Result: Negative (no AMA detected).

Positive Result: Presence of AMA → strongly suggests primary biliary cholangitis.

Clinical Use:

Confirms autoimmune liver disease (especially PBC).

Helps differentiate between autoimmune and non-autoimmune liver conditions.

Guides treatment and monitoring of chronic liver disease.