eGFR is calculated from serum creatinine levels, age, sex, and sometimes race.

It reflects the rate at which the kidneys filter blood through the glomeruli.

Clinical uses include:

Detecting early kidney disease.

Monitoring progression of chronic kidney disease (CKD).

Guiding treatment decisions for kidney-related conditions.

Adjusting medication dosages that depend on kidney clearance.

The test is performed using a blood sample (serum creatinine).

Analyte: Estimated glomerular filtration rate (based on serum creatinine).

Normal Range: ~90–120 mL/min/1.73 m² (varies slightly by lab).

Interpretation:

≥ 90: Normal kidney function.

60–89: Mildly decreased function (may be early CKD if other markers present).

30–59: Moderate CKD.

15–29: Severe CKD.

< 15: Kidney failure (end-stage renal disease).

Clinical Use:

Detects reduced kidney function.

Monitors CKD progression.

Guides nephrology referral and treatment planning.