Immunoglobulin E (IgE) is an antibody produced by the immune system in response to allergens.

Elevated IgE levels are commonly associated with allergic reactions, asthma, and atopic conditions.

Clinical uses include:

Diagnosing and monitoring allergic diseases (hay fever, eczema, food allergies).

Supporting evaluation of asthma severity.

Detecting parasitic infections (which can also raise IgE levels).

Assessing immune system disorders.

Often performed alongside specific allergen IgE tests to identify triggers.

Analyte: Serum IgE concentration (IU/mL).

Normal Range (varies by age and lab):

Children: < 60 IU/mL

Adults: < 100–150 IU/mL

Abnormal Findings:

High IgE: Suggests allergic conditions, asthma, eczema, parasitic infections, or immunodeficiency syndromes (e.g., Hyper‑IgE syndrome).

Low/Normal IgE: Usually indicates absence of significant allergic or parasitic activity.

Clinical Use:

Provides a general marker of allergic sensitivity.

Helps guide allergy management and treatment.

Supports diagnosis of immune and parasitic disorders.