LDL cholesterol (“bad” cholesterol): Contributes to plaque buildup in arteries, increasing risk of heart disease.

HDL cholesterol (“good” cholesterol): Helps remove excess cholesterol from blood vessels, offering protection against heart disease.

The LDL/HDL ratio provides a more accurate measure of cardiovascular risk than either value alone.

Clinical uses include:

Assessing risk of atherosclerosis, coronary artery disease, and stroke.

Monitoring patients on lipid‑lowering therapy.

Supporting preventive health screening.

Often performed alongside total cholesterol and triglycerides as part of a lipid profile.

Analytes: LDL cholesterol (mg/dL), HDL cholesterol (mg/dL), and their ratio.

Normal Range (varies by lab):

LDL/HDL ratio: Ideally < 3.0

Abnormal Findings:

High LDL/HDL ratio (>3.5): Increased risk of cardiovascular disease.

Low LDL/HDL ratio (<2.0): Lower risk, generally favorable lipid profile.

Clinical Use:

Provides a marker of cardiovascular risk.

Helps guide dietary, lifestyle, and pharmacological interventions.

Supports long‑term monitoring of lipid disorders.