Leptospirosis is a bacterial infection caused by Leptospira species, commonly spread through contact with urine of infected animals.

The IgM antibody indicates recent or acute infection, while IgG antibody suggests past exposure or chronic infection.

Clinical uses include:

Confirming diagnosis in patients with fever, muscle pain, jaundice, or kidney/liver involvement.

Differentiating between acute and past infection.

Supporting epidemiological studies in endemic areas.

The test is performed using a blood sample and analyzed by ELISA or other immunoassay methods.

Analyte: IgG and IgM antibodies against Leptospira bacteria.

Result Interpretation:

IgM Positive: Suggests recent/active leptospira infection.

IgG Positive: Indicates past exposure or late-stage infection.

Both Positive: May suggest ongoing or recent infection with immune response.

Clinical Use:

Detects leptospirosis in suspected cases.

Differentiates acute vs past infection.

Supports diagnosis alongside clinical symptoms and other lab findings (CBC, LFT, RFT).