PTH regulates calcium and phosphate balance by acting on bones, kidneys, and intestines.

Clinical uses include:

Diagnosing hyperparathyroidism (overactive parathyroid glands).

Detecting hypoparathyroidism (underactive parathyroid glands).

Evaluating calcium metabolism disorders.

Monitoring patients with chronic kidney disease (CKD) for secondary hyperparathyroidism.

Supporting diagnosis of osteoporosis and bone metabolism disorders.

Often performed alongside serum calcium, phosphate, and vitamin D tests for a complete metabolic profile.

Analyte: Serum Parathyroid Hormone (pg/mL).

Normal Range (varies by lab): ~10–65 pg/mL.

Abnormal Findings:

High PTH: Primary hyperparathyroidism, secondary hyperparathyroidism (CKD, vitamin D deficiency), paraneoplastic syndromes.

Low PTH: Hypoparathyroidism, post‑thyroid/parathyroid surgery, autoimmune disease.

Clinical Use:

Provides a marker of parathyroid gland function.

Helps guide management of calcium and bone disorders.

Supports renal and endocrine evaluations.