The TORCH panel evaluates maternal immunity and prior exposure to infections that can cause congenital abnormalities or miscarriage.

IgG antibodies indicate past infection or immunity (not acute infection).

Clinical uses include:

Screening pregnant women for risk of congenital infections.

Determining immune status (e.g., rubella immunity before or during pregnancy).

Supporting diagnosis of previous exposure to toxoplasmosis, CMV, HSV, or rubella.

Differentiating between acute vs. past infection when combined with IgM testing.

Often performed alongside TORCH IgM panel for comprehensive evaluation.

Analytes: IgG antibodies against:

Toxoplasma gondii

Rubella virus

Cytomegalovirus (CMV)

Herpes simplex virus (HSV‑1/HSV‑2)

Other infections (varicella, syphilis, parvovirus B19 depending on panel design)

Normal Result: Negative (no IgG antibodies detected → no prior exposure or immunity).

Abnormal Findings:

Positive IgG: Indicates past infection or immunity.

Negative IgG: No prior exposure; patient may be susceptible to infection.

Clinical Use:

Provides a baseline of maternal immunity.

Helps guide prenatal counseling and preventive measures.

Supports obstetrics, gynecology, and infectious disease evaluations.