Bile salts are normally secreted into the intestine to aid fat digestion and absorption.
In cases of liver disease or bile duct obstruction, bile salts may spill into the bloodstream and be excreted in urine.
Clinical uses include:
Screening for cholestasis and obstructive jaundice.
Supporting diagnosis of hepatocellular disease (e.g., hepatitis, cirrhosis).
Detecting early liver dysfunction in patients with jaundice.
Often performed alongside Urine Bile Pigments, Liver Function Tests (LFTs), and imaging studies for comprehensive evaluation.