Normally, glucose is reabsorbed by the kidneys and absent in urine.
Glycosuria (sugar in urine) occurs when blood glucose exceeds the renal threshold or when renal tubular reabsorption is impaired.
Clinical uses include:
Screening for diabetes mellitus.
Monitoring glycemic control in diabetic patients.
Detecting renal glycosuria (rare condition where kidneys excrete glucose despite normal blood sugar).
Supporting evaluation of pregnancy, endocrine disorders, or metabolic stress.
Often performed alongside blood glucose, HbA1c, and urine ketone tests for comprehensive assessment.